Dang Truong
Mary Gates Research Scholar
Winter 2023
Major: Biology (Bothell Campus)
Mentor: Nathan Sniadecki, Mechanical Engineering
Project
Research Project: Evaluating the Effect of VWF:ADAMTS13 Ratio on Embolization and Thrombotic Risk Using a Microfluidic Device
Using a microfluidic device to explore how the ratio between blood glycoprotein von Willebrand Factor (VWF) and its protease ADAMTS13 regulate hemostasis in platelets, thus gaining an insight into thrombosis and bleeding risk.
What I learned
This research experience had taught me valuable hematology knowledge, laboratory, data analysis and technological skills. Being a part of this research, I learned greatly about how platelet are activated and function in a coagulation cascade, what regulates blood clotting activity, hematologic diseases and their treatment approaches. I also learned about microfluidic device fabrication and even got to improve the fabrication process, something new that I never knew about before going into this experience, and now I got interested in microfluidic devices! In additional, I also learned coding skills and image analysis, which help me develop tool for data analysis.
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