Sahana Subramanian
Mary Gates Research Scholar
Winter 2023
Project
Fabrication of a Vascularized Liver Model to Support Hepatocytes in 3D Culture
I am developing a vascularized liver model using collagen “vessels.” The liver has a unique regenerative capacity, and while the regeneration process has been evaluated, the triggers of the intracellular pathways are not clear. Further research would be beneficial to the improvement of liver disease treatment, and the model I am working on addressed several limitations in the field. Specifically, I integrate vasculature and relevant cell types to develop a more representative model.